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Mrs. Danin-Kreiselman, Biology



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Molecular Biology

Last Update: Aug 2007 (Links are after the Standards)

Standard 4: Genes are a set of instructions encoded in the DNA sequence of 
each organism that specify the sequence of amino acids in proteins 
characteristic of that organism. As a basis for understanding this concept: 

5a: The general structures and functions of DNA, RNA, and protein. 

1d: The central dogma of molecular biology outlines 
the flow of information from transcription of ribonucleic acid (RNA) in the 
nucleus to translation of proteins on ribosomes in the cytoplasm.

4a: The general pathway by which ribosomes synthesize 
proteins, using tRNAs to translate genetic information in mRNA. 

For the Real-time Videos of Transription and Translation: Click 
here, 
choose "Reading the Code", then "Putting it 
together", and clock on the 
videos on the left hand side. Enjoy!
http://www.dnai.org/a/index.html

* 
DNA Replication: Great animation! Simple for context of the 
chromosome 
(Used in class)
http://lpscience.fatcow.com/jwanamaker/animations/DNA%20Lecture.html

ANIMATIONS by NOBEL: Fantastic analogies, short stories and 
accurate 
animations
http://nobelprize.org/medicine/educational/dna/b/replication/index.html

DNA discovery - from "DNA from the Beginning"
http://www.dnaftb.org/dnaftb/19/concept/index.html

* 
DNA replication - See DNA polymerase at work, with the 
replication fork 
(Used in class)
http://www.stolaf.edu/people/giannini/flashanimat/molgenetics/dna-rna2.swf

"DNA from the Beginning" - DNA, RNA and Proteins: 
Animations, Scientists and 
more and more....
http://www.dnaftb.org/dnaftb/15/concept/

DNA replication Animation - Also clear and simple (not used in 
class)
http://www.fed.cuhk.edu.hk/~johnson/teaching/genetics/animations/dna_replication.htm

DNA and RNA structures - clear comparison
http://www.accessexcellence.org/AB/GG/rna.html

* 
Animation of transcription and translation
http://lpscience.fatcow.com/jwanamaker/animations/Protein%20-%20lecture.html

Transcription animation (hk)
http://www.fed.cuhk.edu.hk/~johnson/teaching/genetics/animations/transcription.htm

Translation - Animation
http://www.fed.cuhk.edu.hk/~johnson/teaching/genetics/animations/translation.htm

* 
Transcription - Animation (Nebraska)
http://www-class.unl.edu/biochem/gp2/m_biology/animation/gene/gene_a2.html

* 
Translation (Nebraska)
http://www-class.unl.edu/biochem/gp2/m_biology/animation/m_animations/gene3.swf

Transcription Translation overview (Nebraska)
http://www-class.unl.edu/biochem/gp2/m_biology/animation/m_animations/gene1.swf

Morse Code training - Have fun!
http://www.1728.com/morstest.htm

* 
TRANSCRIPTION ANIMATION - Very good! (Used in class)
http://www.stolaf.edu/people/giannini/flashanimat/molgenetics/transcription.swf

Mutation Tutorial - Great! Follow their instrucitons and learn.
http://www.bbc.co.uk/education/asguru/biology/04genesgenetics/04geneticcode/02mutation/index.shtml

From Wayne's Word: Good Analogies with explanations, simple 
animations and 
quizes. Click on the topics 
you have learned: Up to "Table of Codons & Anticodons"
http://waynesword.palomar.edu/lmexer3.htm

Biography of Francis Crick and for James Watson - click on the 
right panel
http://nobelprize.org/nobel_prizes/medicine/laureates/1962/crick-bio.html

* 
Interactive Translation Exercise: Cute anbd easy, but notice 
that 
an 
important component is missing (was skipped for simplicity)!
http://gslc.genetics.utah.edu/units/basics/transcribe/

* 
DNAi: History, Animation and some interactives
http://www.dnai.org/a/index.html

* 
Try this! It's an interactive from NOVA, guiding you how to read 
a DNA 
sequence of a gene.
http://www.pbs.org/wgbh/aso/tryit/dna/shockwave.html

NOVA Explore a Stretch of Code: An interactive tutorial about 
looking up a 
real gene sequence in chormosomes 1 - see the power of molecular 
biology in 
studying diseases, evolution, gene regulation!
http://www.pbs.org/wgbh/nova/genome/explore.html

Replication: Fast and general, but effective.
http://waynesword.palomar.edu./dnarepl.htm

Animation of Translation - detailed and yet CLEAR!
http://www.johnkyrk.com/DNAtranslation.html

Interactive of transcription with initiation and termination
http://www.indiana.edu/~oso/animations/transcription2.html

Interactive of translation with initiation and termination!!!
http://www.indiana.edu/~oso/animations/translation3.html

Practice Quiz from YOUR TEXTBOOK - DNA replication
http://www.classzone.com/cz/books/bio_07/quiz.htm?title=Section%20Quiz&ch=3&testId=18219

Multiple links to narrated animations about genes, proteins, and 
their effects
http://learn.genetics.utah.edu/content/begin/dna/

Protein Synthesis / Gene Expression interactive FROM YOUR BOOK!
http://www.classzone.com/cz/books/bio_07/resources/htmls/animated_biology/unit3/bio_ch08_0257_ab_protein.html

Practice Quiz from YOUR TEXTBOOK - Gene Expression
http://www.classzone.com/cz/books/bio_07/quiz.htm?title=Section%20Quiz&ch=3&testId=18220

A Quick and helpful animation showing the connection between 
chrosomeoms to 
nucleotides.
http://www.ornl.gov/sci/techresources/Human_Genome/publicat/twistedladder/inter1.html

Animations from Tokyo Medical University - including chromosomal 
mapping, 
mutations and more and more.
http://www.tokyo-med.ac.jp/genet/index-e.htm

Dolan DNA Animations (including SIckle Cell anemia imaging)
http://www.dnalc.org/resources/3d/10-triplet-code.html

THE CENTRAL DOGMA SONG - from UCLA CityLab!!!!
http://www.youtube.com/watch?v=_Q2Ba2cFAew&feature=related

Review the Basics: From Gene to Protein to Trait
http://learn.genetics.utah.edu/content/begin/tour/

Text, figures and cute animation of the translation process.
http://www.nature.com/scitable/topicpage/the-information-in-dna-determines-cellular-function-6523228

"Journey Into DNA" - Zooming in from a whole human to the DNA 
through all levels of organization.
http://ca.pbslearningmedia.org/content/foa10.sci.living.gen.lpdreamgen/#content/4dd2f8d8add2c73bce0043cd


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